Chemical name: 1,1'-Biphenyl, chloro derivs. Final regulatory action has been taken for the category: Industrial Final regulatory action: The chemical is Banned Use or uses prohibited by the final regulatory action: Polychlorinated biphenyls is prohibited/banned for all uses. The final regulatory action was based on a risk or hazard evaluation: No Summary of the final regulatory action: Based on Government Regulation No. 74 Year 2001 on Hazardous Substances Management, the use of PCBs has been banned for manufacture, import, export, and use as both industrial and agricultural purposes. No remaining uses are allowed. Human studies have shown that PCBs exposure leads to skin abnormalities (acneform). Accidental poisoning suggests that effects may be retardation of foetal growth and alteration on fetal growth retardation and alteration of calcium metabolism related to hormonal disfunction. Clinical sign of short-term Toxicity include effects on reproduction, teratogenicity, immune alteration, liver damage, increase of microsomal enzyme activity, interference with steroid metabolism. The reasons for the final regulatory action were relevant to: Date of entry into force of the final regulatory action: 26/05/2002 |